SCHEMBL5716262

SCHEMBL5716262

CCCCCCC(F)(F)C(F)(F)C(F)(F)NCCCC.Fc1ccccc1-c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.33
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC2 Q92769 2/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GNRHR P30968 1/20 0.31
TLR8 Q9NR97 1/20 0.31
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440133 0.95 GCGR (0.33) GCGRSMN1; SMN2MEN1KMT2AGNRHR
SCHEMBL5716459 0.95 GCGR (0.33) GCGRSMN1; SMN2MEN1KMT2AGNRHR
SCHEMBL5716157 0.89 GCGR (0.35) GCGRSMN1; SMN2MEN1KMT2AGNRHR
SCHEMBL5716423 0.88 GCGR (0.34) GCGRGNRHRTLR8
SCHEMBL5715859 0.86 EPHX2 (0.34)
SCHEMBL5716529 0.84 EPHX2 (0.37)
Biphenyl SCHEMBL5716370 0.80 HDAC3 (0.37) HDAC3HDAC1HDAC2HDAC8
SCHEMBL5715860 0.80 CES2 (0.30)
SCHEMBL5716021 0.79 GCGR (0.33) GCGRGNRHRTLR8
SCHEMBL5715899 0.79 GCGR (0.33) GCGRGNRHRTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed