SCHEMBL5716282

SCHEMBL5716282

CCCCCCCCCN(c1ccc(F)cc1F)C(F)(F)C(F)(F)C(F)(F)CCCCCC

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.35
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
PPARG P37231 3/20 0.32
PPARA Q07869 3/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6440771 1.00 SOAT1 (0.35) SOAT1SLC6A2SLC6A4PPARGPPARA
SCHEMBL5716146 0.90 SOAT1 (0.33) SOAT1SLC6A2SLC6A4PPARGPPARA
SCHEMBL6793616 0.88 SOAT1 (0.36) SOAT1SLC6A2SLC6A4PPARGPPARA
SCHEMBL6790125 0.88 SOAT1 (0.34) SOAT1PPARGPPARAPPARD
SCHEMBL5716380 0.87 SOAT1 (0.32) SOAT1SLC6A2SLC6A4
SCHEMBL6787475 0.87 SOAT1 (0.38) SOAT1SLC6A2SLC6A4PPARGPPARA
SCHEMBL5716226 0.83
SCHEMBL6790311 0.81 SLC6A2 (0.36) SOAT1SLC6A2SLC6A4
SCHEMBL5716597 0.81 SLC6A2 (0.31) SLC6A2SLC6A4
SCHEMBL5715495 0.81 ICMT (0.32) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed