SCHEMBL5716587

SCHEMBL5716587

CCCPCCC.Fc1ccccc1-c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPK1 P28482 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 2/20 0.33
HSP90AA1 P07900 1/20 0.33
ADORA2A P29274 3/20 0.33
ADORA1 P30542 3/20 0.33
DHODH Q02127 2/20 0.33
MAPT P10636 1/20 0.33
TLR8 Q9NR97 1/20 0.32
ADORA3 P0DMS8 2/20 0.31
ADORA2B P29275 1/20 0.31
HTR1A P08908 2/20 0.31
HTR7 P34969 2/20 0.31
GRIA4 P48058 1/20 0.31
USP7 Q93009 1/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715683 0.91 GCGR (0.39) GCGRALDH1A1MAPK1HSD17B10TLR8
SCHEMBL5716067 0.91 GCGR (0.39) GCGRALDH1A1MAPK1HSD17B10TLR8
SCHEMBL5715825 0.90 GCGR (0.39) GCGRALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL5716342 0.87 GCGR (0.40) GCGRALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL5716180 0.84 GCGR (0.35) GCGRALDH1A1MAPK1KDM4EMAPT
SCHEMBL5715827 0.82 GCGR (0.37) GCGRALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL5716123 0.81 GCGR (0.39) GCGRALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL3794433 0.80 DHODH (0.41) ALDH1A1MAPK1KDM4EDHODHMAPT
SCHEMBL5715595 0.79 ADORA2A (0.35) GCGRALDH1A1MAPK1HSD17B10KDM4E
SCHEMBL5716241 0.79 CTSL (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed