Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13538978 | 0.82 | HPGD (0.74) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL1752456 | 0.81 | HPGD (0.66) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL1752455 | 0.81 | HPGD (0.66) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL2206733 | 0.81 | HPGD (0.66) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL13118098 | 0.80 | EPHX2 (0.61) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL5313569 | 0.80 | EPHX2 (0.61) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL5742854 | 0.80 | HPGD (0.70) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL6014610 | 0.79 | HPGD (1.00) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL25176117 | 0.79 | SMN1; SMN2 (0.58) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL12054668 | 0.78 | KEAP1 (0.75) | KDM4EALDH1A1LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558574-A4 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | DIGITAL BIOTECH CO., LTD. (KR) | 2005-12-29 | — | — | US | disclosed |
| EP-1558574-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Digital Biotech Co., Ltd. (KR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004035533-A1 | NOVEL N-HYDROXY THIOUREA, UREA AND AMIDE COMPOUNDS AND THE PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | DIGITAL BIOTECH CO., LTD. (KR) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288369-A1 | Novel n-hydroxy thiourea, urea and amide compounds and the pharmaceutical compositions comprising the same | HRH2, HRH4, NMUR2 | KDM4E 3793/4885ALDH1A1 1397/4885LMNA 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.