Cajanol

Cajanol

SCHEMBL571648

COc1cc(O)c2c(c1)OCC(c1ccc(O)cc1OC)C2=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.53
DYRK1A Q13627 1/20 0.46
ALOX15 P16050 2/20 0.46
ALOX12 P18054 2/20 0.46
CYP19A1 P11511 2/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 2/20 0.44
HPGD P15428 2/20 0.44
USP2 O75604 1/20 0.44
TP53 P04637 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TAS2R31 P59538 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688602 0.81 PTPN1 (0.55) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
(3R)-Sativanone SCHEMBL29576626 0.80 PTPN1 (0.61) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
(3R)-Sativanone SCHEMBL30635254 0.80 PTPN1 (0.61) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
SCHEMBL572085 0.80 PTPN1 (0.67) PTPN1DYRK1ACYP19A1ALDH1A1MAPT
SCHEMBL6142399 0.80 CYP19A1 (0.65) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
SCHEMBL29737519 0.77 TDP1 (0.53) PTPN1ALOX12CYP19A1MEN1KMT2A
SCHEMBL31238344 0.77 PTPN1 (0.56) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
SCHEMBL30561814 0.75 PTPN1 (0.60) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
SCHEMBL213646 0.75 PTPN1 (0.60) PTPN1ALOX15ALOX12CYP19A1ALDH1A1
Dihydrobiochanin A SCHEMBL30217535 0.75 ALOX12 (0.67) PTPN1ALOX15ALOX12CYP19A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119925454-A Application of cajan leaf in rats with chronic myelosuppression caused by MTX 浙江中医药大学 2025-05-06 CN claimed
CN-102731460-A Method for separating and purifying cajanol from pigeon pea rhizomes UNIV NORTHEAST FORESTRY 2012-10-17 CN claimed
CN-119925454-A Application of cajan leaf in rats with chronic myelosuppression caused by MTX 浙江中医药大学 2025-05-06 CN disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
US-20190275119-A1 PROOXIDANT CANCER CHEMO-SUPPRESSORS AND CHEMO-PROTECTORS AND METHODS OF USE RELATED THERETO HOWES RANDOLPH M (US) 2019-09-12 US disclosed
WO-2017065516-A1 COMPOSITION FOR PREVENTING OR TREATING GYNECOLOGICAL CANCERS AND MENOPAUSAL SYMPTOMS CONTAINING CAJANUS CAJAN EXTRACT OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2017-04-20 WO disclosed
WO-2017065516-A1 COMPOSITION FOR PREVENTING OR TREATING GYNECOLOGICAL CANCERS AND MENOPAUSAL SYMPTOMS CONTAINING CAJANUS CAJAN EXTRACT OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2017-04-20 WO disclosed
US-20140234271-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2014-08-21 US disclosed
US-8748177-B2 Compositions for proliferation of cells and related methods THE HOSPITAL FOR SICK CHILDREN (CA) 2014-06-10 US disclosed
EP-2598150-A2 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS The Hospital For Sick Children (CA) 2013-06-05 EP disclosed
CN-102731460-A Method for separating and purifying cajanol from pigeon pea rhizomes UNIV NORTHEAST FORESTRY 2012-10-17 CN disclosed
CN-102731460-A Method for separating and purifying cajanol from pigeon pea rhizomes UNIV NORTHEAST FORESTRY 2012-10-17 CN disclosed
WO-2012018643-A2 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2012-02-09 WO disclosed
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2011-12-08 US disclosed
CN-101497594-B Method for extracting, separating and purifying genistein from pigeon pea rhizome UNIV NORTHEAST FORESTRY 2011-03-23 CN disclosed
CN-101172948-B Method for separation and purification of cajanine and pinostrobin from extract of cajanus cajan branches and leaves UNIV NORTHEAST FORESTRY 2010-09-22 CN disclosed
WO-2010039679-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS THE HOSPITAL FOR SICK CHILDREN (CA) 2010-04-08 WO disclosed
CN-101497594-A Method for extracting, separating and purifying genistein from pigeon pea rhizome UNIV NORTHEAST FORESTRY (CN) 2009-08-05 CN disclosed
WO-2008100977-A2 CARBAMATES THERAPEUTIC RELEASE AGENTS AS AMIDASE INHIBITORS N.V. ORGANON (NL) 2008-08-21 WO disclosed
CN-101172948-A Method for separation and purification of cajanine and pinostrobin from extract of cajanus cajan branches and leaves UNIV NORTHEAST FORESTRY (CN) 2008-05-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140234271-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS MKI67, KRT18, PROX1 PTPN1 3544/4885DYRK1A 2852/4885ALOX15 3682/4885
US-20110301105-A1 COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS MKI67, KRT18, PROX1 PTPN1 3544/4885DYRK1A 2852/4885ALOX15 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.