SCHEMBL5716487

SCHEMBL5716487

CCCN(CCC)c1cccc(F)c1F

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
MAPT P10636 1/20 0.38
DRD2 P14416 1/20 0.36
DRD3 P35462 1/20 0.36
CRHR1 P34998 8/20 0.35
ALDH3A1 P30838 2/20 0.34
ALDH1A3 P47895 2/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715755 0.92 ESR1 (0.37) ESR1MAPTDRD2DRD3ALDH1A1
SCHEMBL6798338 0.90 MEN1 (0.36) ESR1MAPTDRD2DRD3CRHR1
SCHEMBL5716213 0.90 MEN1 (0.36) ESR1MAPTDRD2DRD3CRHR1
SCHEMBL5716044 0.89 NR1H2 (0.39) ESR1DRD2DRD3CRHR1ALDH1A1
SCHEMBL5716207 0.84 NR1H2 (0.37) DRD2DRD3CRHR1ALDH1A1KMT2A
SCHEMBL10620529 0.83 ESR1 (0.47) ESR1MAPTDRD2DRD3CRHR1
SCHEMBL9285999 0.82 ESR1 (0.38) ESR1MAPTDRD2DRD3KMT2A
SCHEMBL5715884 0.82 ESR1 (0.38) ESR1DRD2DRD3ALDH1A1KMT2A
SCHEMBL5716102 0.80 NR1H2 (0.37) ESR1DRD2DRD3CRHR1ALDH1A1
SCHEMBL6790356 0.78 SMN1; SMN2 (0.36) MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed