SCHEMBL6798338

SCHEMBL6798338

CCCCCCCCCN(CCC)c1cccc(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
DRD2 P14416 1/20 0.35
DRD3 P35462 1/20 0.35
CRHR1 P34998 5/20 0.34
KCNH2 Q12809 2/20 0.34
ICMT O60725 2/20 0.34
ESR1 P03372 1/20 0.34
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716213 1.00 MEN1 (0.36) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL5716207 0.95 NR1H2 (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL5716044 0.90 NR1H2 (0.39) MEN1KMT2ASMN1; SMN2ALDH1A1DRD2
SCHEMBL5716487 0.90 ESR1 (0.39) KMT2AALDH1A1DRD2DRD3CRHR1
SCHEMBL5715811 0.89 MEN1 (0.35) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL5715755 0.83 ESR1 (0.37) KMT2ASMN1; SMN2ALDH1A1TP53DRD2
SCHEMBL10621236 0.83 KCNH2 (0.41) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL5715959 0.82 MEN1 (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL5715946 0.82 MEN1 (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1TP53
SCHEMBL5716102 0.82 NR1H2 (0.37) MEN1KMT2ASMN1; SMN2ALDH1A1DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed