SCHEMBL5716591

SCHEMBL5716591

CN(C)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 1/20 0.34
HCRTR1 O43613 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
THRB P10828 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18546564 0.96 ALDH1A1 (0.35) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL4441224 0.86 MEN1 (0.32) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL5716470 0.85 MEN1 (0.37) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL12310914 0.83 MEN1 (0.39) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL10463428 0.81 MEN1 (0.34) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL22909360 0.81 MEN1 (0.34) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL27761446 0.81 MEN1 (0.31) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL18562077 0.81 MEN1 (0.38) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL17400898 0.81 MEN1 (0.31) ALDH1A1MEN1HCRTR1LMNAMAPT
SCHEMBL12263109 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087600-B Method for synthesizing 1, 4-dimethoxy tetrafluorobenzene 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN claimed
CN-113087600-A Synthesis method of 1, 4-dimethoxy tetrafluorobenzene 张家港市国泰华荣化工新材料有限公司 2021-07-09 CN claimed
CN-113087600-B Method for synthesizing 1, 4-dimethoxy tetrafluorobenzene 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN disclosed
CN-113087600-B Method for synthesizing 1, 4-dimethoxy tetrafluorobenzene 张家港市国泰华荣化工新材料有限公司 2022-05-24 CN disclosed
CN-113087600-A Synthesis method of 1, 4-dimethoxy tetrafluorobenzene 张家港市国泰华荣化工新材料有限公司 2021-07-09 CN disclosed
CN-113087600-A Synthesis method of 1, 4-dimethoxy tetrafluorobenzene 张家港市国泰华荣化工新材料有限公司 2021-07-09 CN disclosed
US-20200185610-A1 ORGANIC ELECTRONIC MATERIAL, INK COMPOSITION, AND ORGANIC ELECTRONIC ELEMENT HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-06-11 US disclosed
EP-2899241-B1 PHOTOPOLYMERIZATION METHOD, INK SET, IMAGE FORMATION METHOD, INK COMPOSITION, AND PHOTOPOLYMERIZATION INITIATOR AND WATER-SOLUBLE BIIMIDAZOLE USED THEREIN FUJIFILM CORP (JP) 2019-08-28 EP disclosed
WO-2017167631-A1 POLYMERIC ORGANIC NANOPARTICLES WITH ENHANCED EMISSION SONY CORPORATION (JP) 2017-10-05 WO disclosed
WO-2017167633-A1 SENSOR FOR THE DETECTION OF BIOMOLECULES SONY CORPORATION (JP) 2017-10-05 WO disclosed
US-9371460-B2 Photopolymerization method, ink set, ink composition, and water-soluble biimidazole FUJIFILM CORPORATION (JP) 2016-06-21 US disclosed
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed
US-6337297-B1 CHROMIUM CATALYST FOR TRIMERIZATION OF ETHYLENE WITH MULTIDENTATE LIGAND OR HALOGEN, CARBOXY GROUP TOSOH CORPORATION (JP) 2002-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE JAK1, SETDB1, CCNI ALDH1A1 561/4885MEN1 4257/4885HCRTR1 4265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.