SCHEMBL5716899

SCHEMBL5716899

CC1=CC2CC3C=CC=CC3C2C=C1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6761032 0.69 ALDH1A1 (0.43) ALDH1A1
SCHEMBL19827927 0.67
SCHEMBL9242547 0.65
Hydrochloric Acid SCHEMBL19469144 0.64
SCHEMBL19827926 0.60
SCHEMBL1496265 0.60
SCHEMBL26772227 0.60
SCHEMBL16418074 0.60
SCHEMBL9467054 0.60
SCHEMBL22871561 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337501-B1 PROCESS FOR PREPARING 1-INDANONES AKZO NOBEL NV (NL) 2006-12-20 EP disclosed
EP-1337501-A1 PROCESS FOR PREPARING 1-INDANONES Akzo Nobel N.V. (NL) 2003-08-27 EP disclosed
US-6548710-B2 Reacting ketone compound with chlorinating agent, followed by reaction with a friedel-crafts catalyst to produce 1-indanone compound AKZO NOBEL N.V. (NL) 2003-04-15 US disclosed
US-20020077507-A1 Process for preparing 1-indanones AKZO NOBEL N.V. (NL) 2002-06-20 US disclosed
WO-2002036537-A1 PROCESS FOR PREPARING 1-INDANONES AKZO NOBEL N.V. (NL) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077507-A1 Process for preparing 1-indanones CYP1A1, CYP2F1, CYP1B1 ALDH1A1 240/4885MAPT 4738/4885HTT 1529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.