Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4369293 | 0.85 | CNR1 (0.44) | CNR1CNR2MEN1KMT2AMAPT | |
| SCHEMBL3988967 | 0.84 | CNR1 (0.43) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL4378816 | 0.79 | CNR1 (0.46) | CNR1CNR2MEN1KMT2AEPHX2 | |
| SCHEMBL3986351 | 0.79 | SLC6A2 (0.42) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL3989382 | 0.79 | SLC6A2 (0.42) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL3984639 | 0.79 | SLC6A2 (0.42) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL3987300 | 0.79 | SLC6A2 (0.42) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL3983902 | 0.78 | LMNA (0.38) | CNR1CNR2MEN1KMT2ANPC1 | |
| SCHEMBL4362932 | 0.77 | DPP4 (0.42) | — | |
| SCHEMBL3983897 | 0.77 | KMT2A (0.37) | CNR1CNR2MEN1KMT2AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687288-A1 | SUBSTITUTED ARYL CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE | Wyeth (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005037809-A1 | SUBSTITUTED ARYL CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2005-04-28 | — | — | WO | disclosed |