Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | JUN | P05412 | 1/20 | 0.72 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.64 |
| ▸ | TNKS | O95271 | 1/20 | 0.64 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.64 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL333510 | 1.00 | NFKB1 (0.72) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL333511 | 1.00 | NFKB1 (0.72) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL7439430 | 0.98 | NFKB1 (0.69) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL7439425 | 0.98 | NFKB1 (0.69) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL7978817 | 0.96 | NFKB1 (0.67) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL7978810 | 0.96 | NFKB1 (0.67) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL7978819 | 0.96 | NFKB1 (0.67) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL7978812 | 0.96 | NFKB1 (0.67) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL11826842 | 0.88 | HCAR2 (0.57) | NFKB1JUNHCAR2HDAC1HDAC6 | |
| SCHEMBL11826834 | 0.88 | HCAR2 (0.57) | NFKB1JUNHCAR2HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109179623-B | Positively charged Fe3+/Fe2+Method for removing organic pollutants with negative electricity in water by using MOFs activated persulfate | 湖南工程学院 | 2020-04-28 | — | — | CN | disclosed |
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20060211636-A1 | Macrolide Antibiotics | ALIHODZIC SULEJMAN | 2006-09-21 | — | — | US | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | NFKB1 757/4885JUN 3918/4885HCAR2 1263/4885 |
| US-20060211636-A1 | Macrolide Antibiotics | IL1R1, MRPL12, RPS21 | NFKB1 757/4885JUN 3918/4885HCAR2 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.