Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL31509470 | 1.00 | KMO (0.58) | KMOSLC18A3CYP11B2KDM4EHAO1 | |
| Bicarbonate SCHEMBL4410582 | 0.91 | KMO (0.61) | KMOSLC18A3CYP11B2KDM4EHAO1 | |
| Bicarbonate SCHEMBL4407651 | 0.91 | KMO (0.61) | KMOSLC18A3CYP11B2KDM4EHAO1 | |
| Bicarbonate SCHEMBL9436080 | 0.91 | KMO (0.61) | KMOSLC18A3CYP11B2KDM4EHAO1 | |
| Bicarbonate SCHEMBL4412934 | 0.89 | KMO (0.58) | KMOSLC18A3HAO1AKR1C3AKR1C1 | |
| Carbamic Acid SCHEMBL9679981 | 0.89 | AKR1C3 (0.59) | KMOSLC18A3KDM4EAKR1C3AKR1C1 | |
| Hydrogen Peroxide SCHEMBL42934 | 0.89 | SLC18A3 (0.61) | KMOSLC18A3CYP11B2SMN1; SMN2CYP2D6 | |
| Hydrogen Peroxide SCHEMBL5901852 | 0.89 | SLC18A3 (0.61) | KMOSLC18A3CYP11B2SMN1; SMN2CYP2D6 | |
| Hydrogen Peroxide SCHEMBL9997756 | 0.89 | SLC18A3 (0.61) | KMOSLC18A3CYP11B2SMN1; SMN2CYP2D6 | |
| Hydrogen Peroxide SCHEMBL2352896 | 0.89 | SLC18A3 (0.61) | KMOSLC18A3CYP11B2SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318977-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| EP-1318977-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-12-06 | — | — | EP | disclosed |
| EP-1187812-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| EP-1187812-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| EP-1436273-A1 | SUBSTITUTED PIPERAZINE CYCLOHEXANE CARBOXILIC ACID AMIDES AND THE USE THEREOF | Bayer HealthCare AG (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1318977-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | Bayer Aktiengesellschaft (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-1318977-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | Bayer Aktiengesellschaft (DE) | 2003-06-18 | — | — | EP | disclosed |
| EP-1185516-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES THAT HAVE AN ADENOSINE UPTAKE INHIBITING EFFECT | BAYER AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| EP-1185516-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES THAT HAVE AN ADENOSINE UPTAKE INHIBITING EFFECT | BAYER AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-2003033484-A1 | SUBSTITUTED PIPERAZINE CYCLOHEXANE CARBOXILIC ACID AMIDES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2003-04-24 | — | — | WO | disclosed |
| EP-1187812-A2 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | Bayer Aktiengesellschaft (DE) | 2002-03-20 | — | — | EP | disclosed |
| WO-2002020472-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| WO-2002020472-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THE USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| EP-1185516-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES THAT HAVE AN ADENOSINE UPTAKE INHIBITING EFFECT | Bayer Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-1185516-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES THAT HAVE AN ADENOSINE UPTAKE INHIBITING EFFECT | Bayer Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000073274-A3 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER AG (DE) | 2001-04-19 | — | — | WO | disclosed |
| WO-2000073274-A2 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000073275-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES THAT HAVE AN ADENOSINE UPTAKE INHIBITING EFFECT | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000073275-A1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES THAT HAVE AN ADENOSINE UPTAKE INHIBITING EFFECT | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000073274-A2 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-07 | — | — | WO | disclosed |