Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.62 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780860 | 0.96 | TSHR (0.67) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL19712876 | 0.94 | TSHR (0.59) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL6133308 | 0.94 | TSHR (0.64) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL7207107 | 0.92 | TSHR (0.62) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL3414119 | 0.92 | TSHR (0.66) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL8519821 | 0.92 | TSHR (0.54) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL6133219 | 0.90 | TSHR (0.59) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL5025197 | 0.89 | TSHR (0.58) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL7263921 | 0.89 | TSHR (0.58) | TSHRHCAR2HPGDTDP1CYP3A4 | |
| SCHEMBL6915106 | 0.88 | TSHR (0.57) | TSHRHCAR2HPGDTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332193-B1 | ADHESIVE COMPOSITION AND ADHESIVE SHEET | 3M INNOVATIVE PROPERTIES CO (US) | 2006-12-27 | — | — | EP | claimed |