SCHEMBL5718152

SCHEMBL5718152

N#Cc1ccc(C=Cc2ccc(C=O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 4/20 0.55
ALDH1A1 P00352 3/20 0.49
HDAC2 Q92769 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
P4HB P07237 1/20 0.47
EGFR P00533 2/20 0.47
NR1H3 Q13133 1/20 0.45
HTT P42858 1/20 0.44
SNCA P37840 1/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718150 1.00 FBP1 (0.55) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL10382303 0.94 HDAC2 (0.57) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL7047 0.93 EGFR (0.52) FBP1ALDH1A1HDAC2LMNAMAPT
Water SCHEMBL29120229 0.93 EGFR (0.52) FBP1ALDH1A1HDAC2LMNAMAPT
Hydrochloric Acid SCHEMBL28598774 0.91 EGFR (0.50) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL8699093 0.88 FBP1 (0.59) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL1687898 0.88 FBP1 (0.59) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL1260529 0.88 FBP1 (0.59) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL21574805 0.88 FBP1 (0.59) FBP1ALDH1A1HDAC2LMNAMAPT
SCHEMBL13799049 0.88 FBP1 (0.59) FBP1ALDH1A1HDAC2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210476-B1 MIXTURES OF FLUORESCENT WHITENING AGENTS CIBA SC HOLDING AG (CH) 2006-06-14 EP claimed
US-5072016-A MIXTURES OF FLUORESCENT WHITENING AGENTS CIBA-GEIGY CORPORATION (US) 1991-12-10 US claimed
US-4891153-A Mixtures of fluorescent whitening agents CIBA-GEIGY CORPORATION (US) 1990-01-02 US claimed
EP-0030917-A2 Optical brighteners from bistyryl benzene, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-06-24 EP claimed
JP-1152161-A None JP disclosed
EP-0238446-B1 Mixtures of optical brighteners CIBA GEIGY AG (CH) 1995-11-15 EP disclosed
US-5072016-A MIXTURES OF FLUORESCENT WHITENING AGENTS CIBA-GEIGY CORPORATION (US) 1991-12-10 US disclosed
US-5072016-A MIXTURES OF FLUORESCENT WHITENING AGENTS CIBA-GEIGY CORPORATION (US) 1991-12-10 US disclosed
US-5001253-A Fluorescent brighteners consisting of bis-styrylbenzene compounds, a process for their preparation and their use CIBA-GEIGY CORPORATION (US) 1991-03-19 US disclosed
US-4891153-A Mixtures of fluorescent whitening agents CIBA-GEIGY CORPORATION (US) 1990-01-02 US disclosed
US-4867906-A Mixtures of fluorescent whitening agents CIBA-GEIGY CORPORATION (US) 1989-09-19 US disclosed
US-4867906-A Mixtures of fluorescent whitening agents CIBA-GEIGY CORPORATION (US) 1989-09-19 US disclosed
US-4610807-A FLUORESCENT BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed
EP-0041675-B1 4-HALOGEN-5-(TRICHLOROMETHYL-PHENYL)-OXAZOLE DERIVATIVES, PROCESS FOR PREPARING THEM AND RADIATION-SENSITIVE COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1985-12-11 EP disclosed
EP-0144640-A1 Distyrene compounds BAYER AG (DE) 1985-06-19 EP disclosed
US-4371607-A 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 US disclosed
US-4317782-A DYE LASERS, WHITENERS BAYER AKTIENGESELLSCHAFT (DE) 1982-03-02 US disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed
EP-0030917-A2 Optical brighteners from bistyryl benzene, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-06-24 EP disclosed
EP-0003784-A1 Distyryl compounds, their manufacture and use as bleaching agents and laser dyestuff BAYER AG (DE) 1979-09-05 EP disclosed