Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573894 | 0.93 | RECQL (0.53) | RECQLALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL5718378 | 0.87 | MAPT (0.42) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL5718281 | 0.86 | POLB (0.37) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL5718409 | 0.86 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2GAAMAPT | |
| SCHEMBL5718502 | 0.82 | MAPT (0.43) | ALDH1A1SMN1; SMN2GAAMAPTPKM | |
| Water SCHEMBL5718501 | 0.81 | MAPT (0.44) | RECQLALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5718453 | 0.80 | MAPT (0.44) | RECQLALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL5718463 | 0.79 | MAPT (0.53) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL6571751 | 0.79 | MAPT (0.46) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL5718306 | 0.79 | KAT2B (0.46) | ALDH1A1LMNASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018333-B1 | Use of cationic monobenzene nitroanilines for dyeing keratin fibres , compositions and dyeing process | OREAL (FR) | 2006-03-01 | — | — | EP | claimed |
| US-6478827-B1 | Use of cationic monobenzene nitroanilines in the dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'ORéAL S.A. (FR) | 2002-11-12 | — | — | US | claimed |
| US-6638321-B1 | Oxidation color dyes for hair from aniline compounds | L'OREAL (FR) | 2003-10-28 | — | — | US | disclosed |
| US-6478827-B1 | Use of cationic monobenzene nitroanilines in the dyeing of keratinous fibers, dyeing compositions and dyeing processes | L'ORéAL S.A. (FR) | 2002-11-12 | — | — | US | disclosed |