Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 16/20 | 0.66 |
| ▸ | KDM6B | O15054 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | KDM4A | O75164 | 2/20 | 0.66 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.66 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.59 |
| ▸ | CDC7 | O00311 | 2/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.57 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1714819 | 0.87 | KDM4C (0.85) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL5718299 | 0.84 | CDC7 (0.64) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL1715953 | 0.83 | KDM4C (0.61) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL27847518 | 0.78 | KDM4C (0.67) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL1715363 | 0.78 | KDM4C (0.64) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL5718586 | 0.77 | KDM4C (0.66) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL15839861 | 0.77 | KDM4C (0.78) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL3860684 | 0.77 | KDM4C (0.51) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL12280211 | 0.77 | CDC7 (0.53) | KDM4CKDM6BKDM4EKDM4AKDM4D | |
| SCHEMBL429479 | 0.77 | KDR (0.66) | KDM4CKDM6BKDM4EKDM4AKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |