Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378184 | 0.83 | KMT2A (0.83) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL7700654 | 0.82 | MEN1 (0.69) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL15480439 | 0.81 | MEN1 (0.68) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL18660186 | 0.81 | MEN1 (0.68) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL9212983 | 0.81 | ALDH1A1 (0.63) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL9018657 | 0.80 | MEN1 (0.71) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL7121725 | 0.80 | KMT2A (0.70) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL7640355 | 0.80 | MEN1 (0.70) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL3262054 | 0.80 | MEN1 (0.63) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL1429699 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298135-B1 | Dyeing composition containing silyl substituted p-aminophenol or p-phenylenediamine | OREAL (FR) | 2006-08-16 | — | — | EP | disclosed |
| US-7018427-B2 | Dyeing composition containing a para-aminophenol or para-phenylenediamine compound substituted with a silane radical | L'OREAL S.A. (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20030150066-A1 | Dyeing composition containing a para-aminophenol or para-phenylenediamine compound substituted with a silane radical | L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | disclosed |
| EP-1298135-A1 | Dyeing composition containing silyl substituted p-aminophenol or p-phenylenediamine | L'OREAL (FR) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030150066-A1 | Dyeing composition containing a para-aminophenol or para-phenylenediamine compound substituted with a silane radical | KRT18, CDC73, S100P | MEN1 4558/4885KMT2A 1204/4885MAPT 934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.