Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 20/20 | 0.41 |
| ▸ | LOX | P28300 | 10/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331582 | 0.72 | LOXL2 (0.52) | LOXL2LOXLOXL3 | |
| SCHEMBL2642933 | 0.72 | LOXL2 (0.62) | LOXL2LOXLOXL3 | |
| SCHEMBL6181378 | 0.71 | RECQL (0.43) | LOXL2LOXLOXL3 | |
| SCHEMBL4310666 | 0.71 | FGFR4 (0.34) | — | |
| SCHEMBL1490759 | 0.70 | LOXL2 (0.55) | LOXL2 | |
| SCHEMBL8258382 | 0.69 | LOXL2 (0.42) | LOXL2LOXLOXL3 | |
| SCHEMBL17993854 | 0.68 | LOXL2 (0.44) | LOXL2LOXLOXL3 | |
| SCHEMBL8340586 | 0.68 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL2643691 | 0.66 | LOXL2 (0.55) | LOXL2LOXLOXL3 | |
| SCHEMBL1319117 | 0.66 | HRH3 (0.54) | LOXL2LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697312-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | Leo Pharma A/S (DK) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005054179-A2 | HYDROXAMIC ACID ESTERS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2005-06-16 | — | — | WO | disclosed |