Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719333 | 0.87 | NPC1 (0.48) | GAAL3MBTL1ALDH1A1TP53HSD17B10 | |
| SCHEMBL5719154 | 0.87 | ALDH1A1 (0.41) | GAAL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5719594 | 0.86 | GAA (0.41) | GAAL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL2952546 | 0.85 | DPP4 (0.45) | GAAL3MBTL1DPP4 | |
| SCHEMBL5275990 | 0.85 | DPP4 (0.64) | L3MBTL1DPP4 | |
| SCHEMBL5719100 | 0.84 | ALDH1A1 (0.67) | GAAL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5719105 | 0.83 | MAPK1 (0.60) | GAAL3MBTL1ALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5718830 | 0.83 | DPP4 (0.40) | GAAL3MBTL1SMN1; SMN2DPP4MEN1 | |
| SCHEMBL5719172 | 0.83 | DPP4 (0.53) | DPP4 | |
| SCHEMBL5719159 | 0.83 | POLB (0.67) | GAAL3MBTL1ALDH1A1TP53DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20060094722-A1 | Combination drug | EISAI CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | GAA 2197/4885L3MBTL1 1200/4885ALDH1A1 112/4885 |
| US-20060094722-A1 | Combination drug | DPP4, GLP1R, DPP7 | GAA 183/4885L3MBTL1 4196/4885ALDH1A1 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.