Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5719005 | 0.96 | DPP4 (0.44) | DPP4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL5791755 | 0.94 | DPP4 (0.42) | DPP4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL5719064 | 0.92 | DPP4 (0.40) | DPP4ALDH1A1CNR1IRAK4ADRB1 | |
| Trifluoroacetic Acid SCHEMBL5718979 | 0.92 | DPP4 (0.41) | DPP4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL5719566 | 0.91 | DPP4 (0.42) | DPP4ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL5719420 | 0.90 | DPP4 (0.41) | DPP4ALDH1A1HSD17B10LMNAIRAK4 | |
| Trifluoroacetic Acid SCHEMBL5719037 | 0.88 | MTOR (0.39) | DPP4ALDH1A1CYP1A2CYP3A4IRAK4 | |
| Trifluoroacetic Acid SCHEMBL5719494 | 0.87 | DPP4 (0.58) | DPP4ALDH1A1HSD17B10USP2LMNA | |
| Trifluoroacetic Acid SCHEMBL5719155 | 0.86 | DPP4 (0.39) | DPP4ALDH1A1CYP1A2CYP3A4LMNA | |
| Trifluoroacetic Acid SCHEMBL5719582 | 0.86 | DPP4 (0.41) | DPP4ALDH1A1HSD17B10CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | DPP4 1/4885ALDH1A1 112/4885HSD17B10 499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.