Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5719064 | 0.92 | DPP4 (0.40) | DPP4DRD2DRD3ALDH1A1DRD4 | |
| Trifluoroacetic Acid SCHEMBL5718979 | 0.91 | DPP4 (0.41) | DPP4ALDH1A1IRAK4KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5719005 | 0.91 | DPP4 (0.44) | DPP4ALDH1A1IRAK4KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5719582 | 0.88 | DPP4 (0.41) | DPP4ALDH1A1KMT2ASMN1; SMN2LMNA | |
| Trifluoroacetic Acid SCHEMBL5718892 | 0.86 | DPP4 (0.42) | DPP4ALDH1A1IRAK4KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL5719244 | 0.86 | DPP4 (0.39) | DPP4ALDH1A1IRAK4KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5791755 | 0.86 | DPP4 (0.42) | DPP4ALDH1A1IRAK4KMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5719037 | 0.85 | MTOR (0.39) | DPP4ALDH1A1IRAK4KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL5719566 | 0.83 | DPP4 (0.42) | DPP4ALDH1A1SMN1; SMN2LMNATP53 | |
| Trifluoroacetic Acid SCHEMBL5718984 | 0.83 | DPP4 (0.47) | DPP4ALDH1A1IRAK4KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074798-B2 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD (JP) | 2006-07-11 | — | — | US | disclosed |
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | EISAI CO., LTD. (JP) | 2004-04-29 | — | — | US | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082570-A1 | Xanthine derivative and DPPIV inhibitor | DPP4, DPP9, DPP7 | DPP4 1/4885DRD2 232/4885DRD3 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.