Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5718941 | 0.92 | DPP4 (0.58) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5719295 | 0.91 | DPP4 (0.66) | DPP4ALDH1A1LMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL5719120 | 0.90 | DPP4 (0.55) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5719360 | 0.89 | DPP4 (0.56) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| SCHEMBL5719124 | 0.89 | DPP4 (0.53) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5719241 | 0.89 | DPP4 (0.57) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5788813 | 0.87 | DPP4 (0.55) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5718835 | 0.87 | DPP4 (0.68) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5719165 | 0.86 | LMNA (0.57) | DPP4L3MBTL1ALDH1A1LMNAHTT | |
| Trifluoroacetic Acid SCHEMBL5719162 | 0.86 | DPP4 (0.66) | DPP4FAPDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-1338595-A2 | Xanthine derivatives as DPP-IV inhibitors | Eisai Co., Ltd. (JP) | 2003-08-27 | — | — | EP | disclosed |