Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.61 |
| ▸ | FAP | Q12884 | 5/20 | 0.57 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5719108 | 0.92 | DPP4 (0.57) | DPP4FAPDPP9CHRM1 | |
| Hydrochloric Acid SCHEMBL5719320 | 0.91 | DPP4 (0.56) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL5719055 | 0.90 | DPP4 (0.74) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL5719377 | 0.87 | DPP4 (0.60) | DPP4FAPDPP9 | |
| Trifluoroacetic Acid SCHEMBL5719285 | 0.87 | DPP4 (0.66) | DPP4FAPDPP9CHRM1 | |
| Hydrochloric Acid SCHEMBL5718883 | 0.87 | DPP4 (0.67) | DPP4FAPDPP9CHRM1 | |
| Hydrochloric Acid SCHEMBL6383664 | 0.87 | DPP4 (0.58) | DPP4FAPDPP9CHRM1HTR2C | |
| Hydrochloric Acid SCHEMBL5776187 | 0.85 | DPP4 (0.58) | DPP4FAPDPP9HTR2C | |
| SCHEMBL5719799 | 0.84 | DPP4 (0.59) | DPP4FAPDPP9CHRM1 | |
| SCHEMBL5790806 | 0.84 | DPP4 (0.51) | DPP4FAPDPP9HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1338595-B1 | Xanthine derivatives as DPP-IV inhibitors | EISAI CO LTD (JP) | 2006-05-03 | — | — | EP | claimed |