Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041 | 1.00 | — | — | |
| SCHEMBL4532450 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4055586 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4525595 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4530049 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4530283 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4533367 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4529308 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL4528477 | 0.96 | TSHR (0.44) | TSHRALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL3392391 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692279-A4 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | MERCK & CO INC (US) | 2006-12-27 | — | — | EP | disclosed |
| EP-1692279-A2 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | Merck & Co., Inc. (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005052116-A2 | PRESERVATIVE-CONTAINING VIRUS FORMULATIONS | MERCK & CO., INC. (US) | 2005-06-09 | — | — | WO | disclosed |