Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373225 | 0.77 | TDP1 (0.43) | FAAHRAB9ATSPOSMN1; SMN2DRD2 | |
| SCHEMBL3374322 | 0.73 | SLC6A2 (0.46) | SLC6A2SLC6A4RAB9ABIRC5 | |
| SCHEMBL3521282 | 0.72 | FAAH (0.42) | SLC6A2FAAHPKMRAB9AMAPT | |
| SCHEMBL3370193 | 0.72 | FAAH (0.50) | FAAHPKMRAB9AMAPTNPY5R | |
| SCHEMBL5145087 | 0.70 | TP53 (0.42) | SLC6A2SLC6A4MAPT | |
| SCHEMBL6331322 | 0.69 | SLC6A2 (0.45) | SLC6A2SLC6A4RAB9ABIRC5 | |
| SCHEMBL9373755 | 0.68 | HSD17B10 (0.44) | SLC6A2SLC6A4PKMRAB9AMAPT | |
| SCHEMBL22800416 | 0.65 | FAAH (0.45) | FAAHPKMRAB9ANPY5R | |
| SCHEMBL22800417 | 0.65 | FAAH (0.45) | FAAHPKMRAB9ANPY5R | |
| SCHEMBL18838116 | 0.65 | FAAH (0.40) | FAAHRAB9AMAPTSMN1; SMN2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682494-A4 | ARALKYL AMINES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2006-11-08 | — | — | EP | disclosed |
| EP-1682494-A1 | ARALKYL AMINES AS CANNABINOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044785-A1 | ARALKYL AMINES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2005-05-19 | — | — | WO | disclosed |