Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721597 | 0.89 | PDK2 (0.34) | PDK2 | |
| SCHEMBL5721399 | 0.85 | — | — | |
| SCHEMBL5721200 | 0.85 | HEXA (0.35) | HEXAHEXBPTGS1PTGS2PDK2 | |
| SCHEMBL5721675 | 0.84 | DHFR (0.32) | PDK2 | |
| SCHEMBL5721472 | 0.83 | HEXA (0.36) | HEXAHEXBPTGS1PTGS2PDK2 | |
| SCHEMBL5721877 | 0.82 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL5721818 | 0.78 | HEXA (0.33) | HEXAHEXBPTGS1PTGS2 | |
| SCHEMBL5721766 | 0.78 | HEXA (0.33) | HEXAHEXBPTGS1PTGS2PDK2 | |
| SCHEMBL5721801 | 0.78 | PDK2 (0.30) | PDK2 | |
| SCHEMBL5721217 | 0.76 | PTPN5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |