Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HEXA | P06865 | 1/20 | 0.30 |
| ▸ | HEXB | P07686 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721567 | 0.91 | IKBKB (0.35) | IKBKBRXRARXRBRXRGDRD2 | |
| SCHEMBL5721151 | 0.89 | IKBKB (0.34) | IKBKBRXRARXRBRXRGDRD2 | |
| SCHEMBL5721474 | 0.87 | IKBKB (0.35) | IKBKBRXRARXRBRXRGS1PR1 | |
| SCHEMBL5721387 | 0.84 | IKBKB (0.40) | IKBKBRXRARXRBRXRGKDM1A | |
| SCHEMBL5721914 | 0.84 | IKBKB (0.31) | IKBKB | |
| SCHEMBL5721328 | 0.83 | PDE2A (0.33) | IKBKB | |
| SCHEMBL5721753 | 0.83 | CTSS (0.34) | IKBKBRXRARXRBRXRGDRD2 | |
| SCHEMBL5721223 | 0.82 | HEXA (0.36) | HEXAHEXB | |
| SCHEMBL5721418 | 0.82 | TACR1 (0.38) | DRD2HTR2AHTR2CCNR1CNR2 | |
| SCHEMBL5721614 | 0.81 | IKBKB (0.34) | IKBKBRXRARXRBRXRGS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1640377-A1 | Metallocenes and catalyst compositions derived therefrom | Exxonmobil Chemical Patents Inc. (US) | 2006-03-29 | — | — | EP | disclosed |