SCHEMBL5721798

SCHEMBL5721798

CCCC1=Cc2c(ccc(C)c2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)[CH]1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 1/20 0.33
RXRB P28702 3/20 0.32
RXRA P19793 2/20 0.32
POLB P06746 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5721567 0.88 IKBKB (0.35) RXRBRXRARXRG
SCHEMBL5721683 0.87 RXRA (0.30) RXRBRXRARXRG
SCHEMBL5721600 0.84
SCHEMBL5721514 0.83 RXRB (0.31) RXRBRXRA
SCHEMBL5721574 0.83 RXRA (0.32) RXRBRXRARXRG
SCHEMBL5721737 0.81
SCHEMBL5721151 0.81 IKBKB (0.34) RXRBRXRARXRG
SCHEMBL1241780 0.80 PTAFR (0.34) RXRBRXRARXRG
SCHEMBL5721482 0.80
SCHEMBL5721493 0.79 POLB (0.34) HTR1DRXRBRXRAPOLBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640377-A1 Metallocenes and catalyst compositions derived therefrom Exxonmobil Chemical Patents Inc. (US) 2006-03-29 EP disclosed