Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.51 |
| ▸ | PPARG | P37231 | 13/20 | 0.51 |
| ▸ | PPARD | Q03181 | 7/20 | 0.51 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5294554 | 0.92 | PPARA (0.53) | PPARAPPARGPPARDFFAR1 | |
| SCHEMBL5721478 | 0.91 | PPARA (0.50) | PPARAPPARGPPARDPOLB | |
| SCHEMBL6255825 | 0.88 | PPARA (0.50) | PPARAPPARGPPARDUTS2RFFAR1 | |
| SCHEMBL5721338 | 0.88 | PPARA (0.54) | PPARAPPARGPPARDPOLB | |
| SCHEMBL5721599 | 0.87 | PPARA (0.49) | PPARAPPARGPPARDUTS2RFFAR1 | |
| Tert-Butylamine SCHEMBL6253908 | 0.85 | PPARA (0.47) | PPARAPPARGPPARDUTS2RFFAR1 | |
| SCHEMBL3968108 | 0.82 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL3959919 | 0.81 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5721594 | 0.80 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL5721665 | 0.80 | PPARA (0.53) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675820-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | AstraZeneca AB (SE) | 2006-07-05 | — | — | EP | claimed |
| WO-2004113270-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | claimed |