Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.53 |
| ▸ | PPARG | P37231 | 14/20 | 0.53 |
| ▸ | PPARD | Q03181 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721338 | 0.91 | PPARA (0.54) | PPARAPPARGPPARDKDM4EALDH1A1 | |
| SCHEMBL5721594 | 0.81 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL3963606 | 0.81 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL4890607 | 0.80 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL3963103 | 0.80 | PPARA (0.59) | PPARAPPARGPPARD | |
| SCHEMBL5721478 | 0.80 | PPARA (0.50) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL5721963 | 0.80 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5294554 | 0.78 | PPARA (0.53) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL6255825 | 0.75 | PPARA (0.50) | PPARAPPARGPPARDGPR34 | |
| Tert-Butylamine SCHEMBL6319866 | 0.75 | PPARA (0.48) | PPARAPPARGPPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675820-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | AstraZeneca AB (SE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2004113270-A2 | PROPIONIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF LIPID DISORDERS | ASTRAZENECA AB (SE) | 2004-12-29 | — | — | WO | disclosed |