⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512605 | 0.75 | — | — | |
| SCHEMBL27847849 | 0.67 | — | — | |
| SCHEMBL7225836 | 0.66 | — | — | |
| SCHEMBL3241529 | 0.66 | — | — | |
| SCHEMBL4512756 | 0.66 | — | — | |
| SCHEMBL9959991 | 0.65 | IDO1 (0.39) | — | |
| SCHEMBL4511998 | 0.64 | IDO1 (0.30) | — | |
| SCHEMBL17766690 | 0.60 | GSK3A (0.36) | — | |
| SCHEMBL4514508 | 0.60 | IDO1 (0.30) | — | |
| SCHEMBL4499393 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006124544-A2 | USE OF TYROSINE KINASE INHIBITORS IN THE TREATMENT OF METABOLIC DISORDERS | NOVARTIS AG (CH) | 2006-11-23 | — | — | WO | disclosed |
| EP-1631291-A2 | USE OF TYROSINE KINASE INHIBITORS TO TREAT DIABETES | Hägerkvist, Robert P. (SE) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004105763-A2 | USE OF TYROSINE KINASE INHIBITOR TO TREAT DIABETES | HAEGERKVIST ROBERT PER (SE) | 2004-12-09 | — | — | WO | disclosed |