SCHEMBL7225836

SCHEMBL7225836

C1=NC=c2ncc3c(c2C1)-c1ccccc1N=3.C1=NCc2c3c(cnc2=C1)=Nc1ccccc1-3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4512605 0.88
SCHEMBL4512756 0.88
SCHEMBL4512007 0.68
SCHEMBL5722147 0.66
SCHEMBL4499393 0.60
SCHEMBL4495883 0.59
SCHEMBL4510411 0.59
SCHEMBL3241529 0.58
SCHEMBL29816457 0.57 IDO1 (0.31)
SCHEMBL1120338 0.57 IDO1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6534496-B1 Prophylactic and/or therapeutic drug for obesity and obesity associated diseasestor diabetes with a reduced risk for central side effects and high universality in usage. Another object of the a lipolytic agent, or a prophylactic and/or TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 2003-03-18 US disclosed