Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4966144 | 0.87 | CNR2 (0.58) | CNR2KCNH2CNR1 | |
| SCHEMBL5722182 | 0.84 | CNR2 (0.69) | CNR2KCNH2CNR1 | |
| SCHEMBL4967744 | 0.83 | CNR2 (0.63) | CNR2KCNH2CNR1 | |
| SCHEMBL5722233 | 0.78 | CNR2 (0.59) | CNR2KCNH2CNR1 | |
| SCHEMBL5722219 | 0.77 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL5722228 | 0.76 | CNR2 (0.55) | CNR2KCNH2 | |
| SCHEMBL17591165 | 0.75 | CNR2 (0.68) | CNR2KCNH2CNR1 | |
| SCHEMBL4965771 | 0.73 | CNR2 (0.72) | CNR2KCNH2CNR1 | |
| SCHEMBL10048956 | 0.72 | CNR2 (0.75) | CNR2KCNH2CNR1 | |
| SCHEMBL3980423 | 0.72 | CNR2 (0.59) | CNR2KCNH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673369-A1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF | AstraZeneca AB (SE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005030761-A1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | disclosed |