Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722219 | 0.92 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL5722233 | 0.91 | CNR2 (0.59) | CNR2KCNH2CNR1 | |
| SCHEMBL4965771 | 0.85 | CNR2 (0.72) | CNR2KCNH2CNR1 | |
| SCHEMBL5722202 | 0.84 | CNR2 (0.57) | CNR2KCNH2CNR1 | |
| SCHEMBL4965990 | 0.83 | CNR2 (0.68) | CNR2KCNH2CNR1 | |
| SCHEMBL5722174 | 0.82 | GNRHR (0.54) | CNR2 | |
| SCHEMBL4966071 | 0.81 | CNR2 (0.64) | CNR2KCNH2CNR1 | |
| SCHEMBL5722228 | 0.81 | CNR2 (0.55) | CNR2KCNH2 | |
| SCHEMBL5521048 | 0.81 | CNR2 (0.62) | CNR2CNR1 | |
| SCHEMBL4966204 | 0.80 | CNR2 (0.71) | CNR2KCNH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673369-A1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF | AstraZeneca AB (SE) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005030761-A1 | BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | disclosed |