Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722468 | 0.92 | KMT2A (0.40) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5717975 | 0.91 | KMT2A (0.39) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5717848 | 0.90 | KMT2A (0.39) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5722567 | 0.89 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5722489 | 0.89 | KMT2A (0.35) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5717871 | 0.88 | KMT2A (0.38) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5722588 | 0.88 | ALDH1A1 (0.35) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5722532 | 0.86 | KMT2A (0.38) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5117906 | 0.86 | HPGD (0.45) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL5718089 | 0.85 | KMT2A (0.36) | KMT2AMEN1MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732532-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS COMPRISING AGONISTS OF THE THYROID RECEPTOR | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092316-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS COMPRISING AGONISTS OF THE THYROID RECEPTOR | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |