Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561237 | 0.91 | NR5A1 (0.47) | NR5A1ALDH2PTPN11RARBMCL1 | |
| SCHEMBL5722766 | 0.87 | PTPN11 (0.43) | NR5A1ALDH2PTPN11RARBMCL1 | |
| SCHEMBL5722635 | 0.85 | TDO2 (0.39) | ALDH2PTPN11RARBMCL1 | |
| SCHEMBL5722784 | 0.84 | NR5A1 (0.39) | NR5A1PTPN11MCL1CNR2TP53 | |
| SCHEMBL5722771 | 0.82 | NR5A1 (0.48) | NR5A1ALDH2RARBMCL1LTA4H | |
| SCHEMBL4866016 | 0.81 | NR5A1 (0.55) | NR5A1PTPN11RARBMCL1LTA4H | |
| SCHEMBL8992927 | 0.81 | NR5A1 (0.55) | NR5A1PTPN11RARBMCL1LTA4H | |
| SCHEMBL9405815 | 0.81 | NR5A1 (0.55) | NR5A1PTPN11RARBMCL1LTA4H | |
| SCHEMBL9493860 | 0.80 | NR5A1 (0.53) | NR5A1PTPN11RARBLTA4HTP53 | |
| SCHEMBL9494141 | 0.80 | NR5A1 (0.56) | NR5A1PTPN11RARBLTA4HTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028944-B1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2006-01-11 | — | — | EP | disclosed |
| US-6491989-B1 | 6,7-DIFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES, 1,1,6,7-TETRAFLUORO-1,2,3,4-TETRAHYDRONAPHTHALENE DERIVATIVES, 1,6,7-TRIFLUORONAPHTHALENE DERIVATIVES AND 2,3-DIFLUORONAPHTHALENE DERIVATIVES | AVENTIS RESEACH & TECHNOLOGIES GMBH & CO. KG (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1028944-A1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999023074-A1 | FLUORINATED NAPHTHALENE DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 1999-05-14 | — | — | WO | disclosed |