Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5722603 | 0.90 | THRA (0.43) | THRATHRB | |
| SCHEMBL5717817 | 0.83 | THRA (0.34) | THRATHRB | |
| SCHEMBL5722492 | 0.83 | THRA (0.42) | THRATHRB | |
| SCHEMBL5722482 | 0.83 | THRA (0.38) | THRATHRB | |
| SCHEMBL5723708 | 0.82 | THRA (0.41) | THRATHRB | |
| SCHEMBL5722574 | 0.82 | THRA (0.35) | THRATHRB | |
| SCHEMBL5718038 | 0.81 | THRA (0.42) | THRATHRB | |
| SCHEMBL5718194 | 0.80 | THRA (0.34) | THRATHRB | |
| SCHEMBL5717855 | 0.80 | THRA (0.41) | THRATHRB | |
| SCHEMBL5722729 | 0.79 | THRA (0.36) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732532-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS COMPRISING AGONISTS OF THE THYROID RECEPTOR | KARO BIO AB (SE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092316-A1 | NOVEL PHARMACEUTICAL COMPOSITIONS COMPRISING AGONISTS OF THE THYROID RECEPTOR | KARO BIO AB (SE) | 2005-10-06 | — | — | WO | disclosed |