Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 9/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837568 | 0.84 | FFAR4 (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6837900 | 0.73 | KMT2A (0.31) | — | |
| SCHEMBL8378241 | 0.72 | PDE4D (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6837783 | 0.72 | PDE4D (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6837995 | 0.71 | LMNA (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6374871 | 0.70 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5722874 | 0.69 | PDE4D (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5723323 | 0.69 | PDE4D (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5723080 | 0.69 | LMNA (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5723066 | 0.68 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771794-B1 | OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO KK (JP) | 2006-05-03 | — | — | EP | disclosed |
| EP-0771794-A1 | OXYGEN-CONTAINING HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-05-07 | — | — | EP | disclosed |