SCHEMBL572298

SCHEMBL572298

COC(=O)/N=C(/NC(=O)OC)SC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12998079 1.00
SCHEMBL572299 1.00
Alcohol SCHEMBL26136185 0.93
SCHEMBL11690047 0.83 ALDH1A1 (0.34)
SCHEMBL11521651 0.83 ALDH1A1 (0.34)
SCHEMBL11690051 0.83 ALDH1A1 (0.34)
SCHEMBL25480034 0.83 SMN1; SMN2 (0.31)
SCHEMBL11317178 0.83
SCHEMBL11317172 0.83
SCHEMBL11641217 0.82 MAPT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12485109-B2 Pyrrolo 12.3-dipyrimidine compounds and analogues thereof BIOCRYST PHARMACEUTICALS, INC. (US) 2025-12-02 US disclosed
US-12485123-B2 1H-pyrazolo[4,3-d]pyrimidine compounds as toll-like receptor 7 (TLR7) agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2025-12-02 US disclosed
US-20250282776-A1 Bicyclic TLR7 Agonists and Uses Thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2025-09-11 US disclosed
US-20250214945-A1 THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2025-07-03 US disclosed
US-20250214987-A1 THIOBENZIMIDAZOLE DERIVATIVE PREPARATION METHOD AND NOVEL INTERMEDIATE THEREFOR KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2025-07-03 US disclosed
WO-2025071191-A1 THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF 고려대학교 산학협력단 2025-04-03 WO disclosed
EP-3889139-B1 COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES CHILDRENS MEDICAL CT CORP (US) 2025-03-19 EP disclosed
WO-2025053634-A1 NOVEL QUINAZOLINE-BENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND USE THEREOF 고려대학교 산학협력단 2025-03-13 WO disclosed
EP-4506346-A1 THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF Korea University Research and Business Foundation (KR) 2025-02-12 EP disclosed
EP-4501915-A1 THIOBENZIMIDAZOLE DERIVATIVE PREPARATION METHOD AND NOVEL INTERMEDIATE THEREFOR Korea University Research and Business Foundation (KR) 2025-02-05 EP disclosed
US-4032655-A PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-06-28 US disclosed
US-4031228-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anti-protozoal activity SYNTEX (U.S.A.) INC. (US) 1977-06-21 US disclosed
US-4024176-A Substituted phenylguanidines and processes for their preparation and use BAYER AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed
US-4005202-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity SYNTEX (U.S.A.) INC. (US) 1977-01-25 US disclosed
US-4002640-A ANTIFUNGAL AGENTS SYNTEX (U.S.A.) INC. (US) 1977-01-11 US disclosed
US-3993682-A Substituted phenylguanidines and processes for their preparation and use BAYER AKTIENGESELLSCHAFT (DT) 1976-11-23 US disclosed
US-3965113-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity SYNTEX (U.S.A.) INC. (US) 1976-06-22 US disclosed
US-3962437-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity SYNTEX (U.S.A.) INC. (US) 1976-06-08 US disclosed
US-3950395-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed
US-3935209-A 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity SYNTEX (U.S.A.) INC. (US) 1976-01-27 US disclosed