Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.76 |
| ▸ | ACE | P12821 | 2/20 | 0.76 |
| ▸ | ECE1 | P42892 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5723089 | 0.86 | ECE1 (1.00) | MMEACEECE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5723260 | 0.84 | MME (0.69) | MMEACEECE1ALDH1A1MMP1 | |
| SCHEMBL5723205 | 0.84 | MME (0.71) | MMEACEECE1POLBELOVL6 | |
| SCHEMBL5722926 | 0.84 | MME (0.77) | MMEACEECE1MMP1 | |
| SCHEMBL5723367 | 0.83 | MME (0.53) | MMEACEECE1POLBALDH1A1 | |
| SCHEMBL5723566 | 0.82 | MME (0.76) | MMEACEECE1MMP1ADAM17 | |
| SCHEMBL5723152 | 0.79 | ECE1 (0.64) | MMEACEECE1POLBELOVL6 | |
| SCHEMBL5723963 | 0.78 | MME (0.68) | MMEACEECE1ALDH1A1MMP1 | |
| SCHEMBL5723300 | 0.78 | ECE1 (0.84) | MMEACEECE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5723412 | 0.76 | MME (0.65) | MMEACEECE1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317428-B1 | PYRROLIDINE-2-CARBOXYLIC ACID HYDRAZIDE DERIVATIVES FOR USE AS METALLOPROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2006-04-19 | — | — | EP | disclosed |