Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | HTR2A | P28223 | 1/20 | 0.77 |
| ▸ | HTR2C | P28335 | 1/20 | 0.77 |
| ▸ | HTR2B | P41595 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702623 | 1.00 | TSHR (0.77) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| SCHEMBL984047 | 1.00 | TSHR (0.77) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Potassium SCHEMBL3500911 | 0.98 | TSHR (0.74) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop SCHEMBL29426474 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop-P SCHEMBL572351 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop-P SCHEMBL29817687 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop SCHEMBL9068516 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop SCHEMBL54983 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop SCHEMBL11349605 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 | |
| Mecoprop SCHEMBL7762943 | 0.87 | TSHR (1.00) | TSHRHTR2AHTR2CHTR2BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612119-A | Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents | 西雅图儿童医院（DBA西雅图儿童研究所） | 2019-12-24 | — | — | CN | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| EP-2099751-B1 | BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS | BAYER IP GMBH (DE) | 2018-05-30 | — | — | EP | claimed |
| EP-2554049-B1 | Herbicidal composition with improved efficiency, preparation method and use | ARD SA (FR) | 2016-03-02 | — | — | EP | claimed |
| US-20160000076-A1 | Fungicidal Active Compound Combinations | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-01-07 | — | — | US | claimed |
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | claimed |
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | claimed |
| US-8993782-B2 | Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-03-31 | — | — | US | claimed |
| EP-2195290-B1 | HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-11 | — | — | EP | claimed |
| US-8709978-B2 | Herbicide composition having improved effectiveness, method of preparation and use | AGRO INDUSTRIE RECHERCHES ET DEVELOPPEMENTS (A.R.D.) (FR) | 2014-04-29 | — | — | US | claimed |
| WO-1997012516-A1 | ADMINISTRATION OF BIOLOGICALLY ACTIVE MATERIAL | INSECT INVESTIGATIONS LIMITED (GB) | 1997-04-10 | — | — | WO | claimed |
| EP-0619946-B1 | Herbicidal composition for upland farming and weeding method | NIHON NOHYAKU CO LTD (JP) | 1996-06-05 | — | — | EP | claimed |
| US-5409885-A | Plant safening agent and nonionic surfactant | RHONE-POULENC CHIMIE (FR) | 1995-04-25 | — | — | US | claimed |
| EP-0639050-A1 | SYNERGISTIC COMPOSITION AND PROCESS FOR SELECTIVE WEED CONTROL | Novartis AG (CH) | 1995-02-22 | — | — | EP | claimed |
| EP-0619946-A1 | Herbicidal composition for upland farming and weeding method | NIHON NOHYAKU CO., LTD. (JP) | 1994-10-19 | — | — | EP | claimed |
| WO-1993021772-A2 | SYNERGISTIC COMPOSITION AND PROCESS FOR SELECTIVE WEED CONTROL | CIBA-GEIGY AG (CH) | 1993-11-11 | — | — | WO | claimed |
| EP-0275556-B1 | HERBICIDAL COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-15 | — | — | EP | claimed |
| EP-0275556-A2 | Herbicidal composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-27 | — | — | EP | claimed |
| EP-0218271-A1 | Synergistic herbicidal compositions and method | STAUFFER CHEMICAL COMPANY (US) | 1987-04-15 | — | — | EP | claimed |
| CN-85101131-A | Novel phenolic ester mixtures | — | 1987-01-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160000076-A1 | Fungicidal Active Compound Combinations | DDT, CYP4X1, CYP51A1 | TSHR 3129/4885HTR2A 2725/4885HTR2C 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.