Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.79 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100120 | 0.90 | F10 (0.80) | F10KLKB1 | |
| SCHEMBL76300 | 0.90 | F10 (0.67) | F10KLKB1 | |
| SCHEMBL3833854 | 0.89 | F10 (0.76) | F10KLKB1 | |
| SCHEMBL3828743 | 0.88 | F10 (0.75) | F10KLKB1 | |
| SCHEMBL3834400 | 0.88 | F10 (0.70) | F10KLKB1 | |
| Eribaxaban SCHEMBL17294640 | 0.88 | F10 (1.00) | F10 | |
| Eribaxaban SCHEMBL76436 | 0.88 | F10 (1.00) | F10 | |
| SCHEMBL3832111 | 0.88 | F10 (0.82) | F10KLKB1 | |
| Eribaxaban SCHEMBL16436969 | 0.88 | F10 (1.00) | F10 | |
| SCHEMBL3835174 | 0.88 | F10 (0.82) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030141-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2006-04-18 | — | — | US | claimed |
| EP-1465864-B1 | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION CASCADE | WARNER LAMBERT CO (US) | 2006-03-15 | — | — | EP | disclosed |