Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24114570 | 1.00 | HRH3 (0.37) | HRH3HRH2HRH1CHRM2CHRM1 | |
| SCHEMBL4089546 | 0.91 | HRH3 (0.40) | HRH3HRH2HRH1 | |
| SCHEMBL4089544 | 0.91 | HRH3 (0.40) | HRH3HRH2HRH1 | |
| Iodide SCHEMBL5786537 | 0.87 | HRH3 (0.41) | HRH3HRH2HRH1 | |
| SCHEMBL4084781 | 0.84 | OPRM1 (0.33) | HRH3HRH2HRH1 | |
| SCHEMBL12371257 | 0.84 | OPRM1 (0.33) | HRH3HRH2HRH1 | |
| SCHEMBL10469227 | 0.84 | HRH3 (0.39) | HRH3HRH2HRH1 | |
| SCHEMBL23828681 | 0.84 | HRH3 (0.41) | HRH3HRH2HRH1 | |
| SCHEMBL23828667 | 0.84 | HRH3 (0.41) | HRH3HRH2HRH1 | |
| SCHEMBL1977537 | 0.79 | GBA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409481-B1 | QUINOLINE DERIVATIVES AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-10-04 | — | — | EP | claimed |
| US-4483833-A | DESULFURIZATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-11-20 | — | — | US | claimed |
| EP-3658522-B1 | IMMUNOMODULATOR COMPOUNDS | CHEMOCENTRYX INC (US) | 2021-12-22 | — | — | EP | disclosed |
| US-20110202328-A1 | System for the determination of selective absorbent molecules through predictive correlations | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-08-18 | — | — | US | disclosed |
| US-20110202328-A1 | System for the determination of selective absorbent molecules through predictive correlations | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2011-08-18 | — | — | US | disclosed |
| WO-1993010883-A1 | LEAN ACID GAS ENRICHMENT WITH SELECTIVE HINDERED AMINES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0087207-B1 | A PROCESS FOR REMOVAL OF H2S FROM GASEOUS STREAMS WITH AMINO COMPOUNDS | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1986-08-06 | — | — | EP | disclosed |
| US-4483833-A | DESULFURIZATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-11-20 | — | — | US | disclosed |
| EP-0087207-A1 | A process for removal of H2S from gaseous streams with amino compounds | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-08-31 | — | — | EP | disclosed |