⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956226 | 0.76 | — | — | |
| SCHEMBL8097848 | 0.76 | — | — | |
| SCHEMBL20811 | 0.75 | — | — | |
| SCHEMBL520066 | 0.74 | — | — | |
| SCHEMBL9004138 | 0.72 | MEN1 (0.44) | — | |
| Fluoride SCHEMBL635228 | 0.72 | — | — | |
| Water SCHEMBL29130541 | 0.72 | — | — | |
| SCHEMBL9983155 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL28633829 | 0.72 | — | — | |
| Ammonia Solution, Strong SCHEMBL4661964 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041197-A | Sertraline side chain tertiary amine structural derivative and preparation method and application thereof | 中国人民解放军陆军军医大学 | 2023-05-02 | — | — | CN | claimed |
| US-20250376473-A1 | PRMTS INHIBITOR AND USE THEREOF | CYTOSINLAB THERAPEUTICS CO LTD (CN) | 2025-12-11 | — | — | US | disclosed |
| CN-119998271-A | Pyridone compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4549442-A1 | PRMT5 INHIBITORS AND USE THEREOF | Cytosinlab Therapeutics Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| EP-4549440-A1 | CLASS OF PRMT5 INHIBITORS AND USE THEREOF | Cytosinlab Therapeutics Co., Ltd. (CN) | 2025-05-07 | — | — | EP | disclosed |
| WO-2025067126-A1 | PYRIDONE COMPOUNDS AND PREPARATION METHOD THEREFOR, AND APPLICATION | 深圳信立泰药业股份有限公司 | 2025-04-03 | — | — | WO | disclosed |
| US-20250092027-A1 | ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICANCER ACTIVITY | ASTEX THERAPEUTICS LIMITED (GB) | 2025-03-20 | — | — | US | disclosed |
| CN-119562954-A | PRMT5 inhibitor and application thereof | 上海赛岚生物科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119487041-A | PRMT5 inhibitor and application thereof | 上海赛岚生物科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-12202828-B2 | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LIMITED (GB) | 2025-01-21 | — | — | US | disclosed |
| US-20010020089-A1 | Purine derivatives | PFIZER INC. | 2001-09-06 | — | — | US | disclosed |
| WO-2001060835-A1 | PURINE DERIVATIVES | PFIZER LIMITED (GB) | 2001-08-23 | — | — | WO | disclosed |
| CN-1262679-A | IL-5 inhibiting 6-azauracil derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2000-08-09 | — | — | CN | disclosed |
| CN-1208415-A | Angiogenesis inhibiting pyridazinamines | JANSSEN PHARMACEUTICA NV (BE) | 1999-02-17 | — | — | CN | disclosed |
| CN-1037268-C | Antipicornaviral pyridazinamines | JANSSEM PHARMACEUTICA N V (BE) | 1998-02-04 | — | — | CN | disclosed |
| CN-1034122-C | Antiviral tetrahydroimioazo [1,4] benzodiazepin-2-(thi) ones | JANSSEN PHARMACEUTICA NV (BE) | 1997-02-26 | — | — | CN | disclosed |
| CN-1029971-C | Process for preparating antiviral tetrahydroimidazo (1,4) benzodiazepines | JANSSEN PHARMACEUTICA NV (BE) | 1995-10-11 | — | — | CN | disclosed |
| CN-1057840-A | New antiviral imidazolidine is [1,4] benzodiazepine-2-(sulphur) ketone also | JANSSEN PHARMACEUTICA NV (BE) | 1992-01-15 | — | — | CN | disclosed |
| CN-1052857-A | The preparation method of the pyridazine amine that antipicornaviral is used | JANSSEN PHARMACEUTICA NV (BE) | 1991-07-10 | — | — | CN | disclosed |
| CN-1050192-A | Prepare the also method of [1,4] benzodiazepine of antiviral imidazolidine | JANSSEN PHARMACEUTICA NV (BE) | 1991-03-27 | — | — | CN | disclosed |