SCHEMBL5724

SCHEMBL5724

NC(=O)c1ccccc1Oc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 1.00
SMN1; SMN2 Q16637 1/20 0.63
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
MAPK1 P28482 1/20 0.55
PARP10 Q53GL7 2/20 0.55
IRAK4 Q9NWZ3 1/20 0.55
SIRT2 Q8IXJ6 1/20 0.54
SIRT1 Q96EB6 1/20 0.54
BRD4 O60885 2/20 0.54
LMNA P02545 3/20 0.51
MAPT P10636 3/20 0.51
NR1I2 O75469 1/20 0.51
CHRM2 P08172 1/20 0.51
CYP3A4 P08684 1/20 0.51
ADRA2A P08913 1/20 0.51
OPRK1 P41145 1/20 0.51
HTR2B P41595 1/20 0.51
SLC6A3 Q01959 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28876495 1.00 CTNNB1 (1.00) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL27680126 1.00 CTNNB1 (1.00) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL28081666 0.98 CTNNB1 (0.96) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
Hydrochloric Acid SCHEMBL50731 0.98 CTNNB1 (0.96) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
Methyl Alcohol SCHEMBL8782982 0.96 CTNNB1 (0.93) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
Hydroquinone SCHEMBL28208693 0.93 CTNNB1 (0.86) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
Trifluoroacetic Acid SCHEMBL5478809 0.90 CTNNB1 (0.81) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL7693879 0.87 CTNNB1 (0.77) CTNNB1SMN1; SMN2MEN1KMT2AIRAK4
SCHEMBL1892492 0.87 CTNNB1 (0.77) CTNNB1SMN1; SMN2MEN1KMT2AMAPK1
SCHEMBL27800575 0.87 CTNNB1 (0.77) CTNNB1SMN1; SMN2MEN1KMT2APARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11037 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727545-A2 COMBINATION TREATMENTS FOR DEPRESSION AND OTHER DISORDERS Neurawell Therapeutics (US) 2026-04-22 EP claimed
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP claimed
US-20250295611-A1 METHODS OF TREATING 5HT2A RECEPTOR-MEDIATED CONDITIONS TESSELLATE THERAPEUTICS INC (US) 2025-09-25 US claimed
EP-4608388-A1 COMBINATORIAL, AND ROTATIONAL COMBINATORIAL THERAPIES FOR OBESITY AND OTHER DISEASES STARROCK PHARMA INC. (US) 2025-09-03 EP claimed
US-20250268841-A1 Trans-Epithelial Membrane Drug Delivery System Masiz, John J. (US) 2025-08-28 US claimed
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2025-08-14 US claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
WO-2025136860-A1 SOLID DRUG RELEASING BIOABSORBABLE PROSTATE IMPLANT FOR BENIGN PROSTATIC HYPERPLASIA RESURGE THERAPEUTICS INC. (US) 2025-06-26 WO claimed
US-20250195414-A1 SOLID DRUG RELEASING BIOABSORBABLE PROSTATE IMPLANT FOR BENIGN PROSTATIC HYPERPLASIA RESURGE THERAPEUTICS INC. 2025-06-19 US claimed
EP-0163237-A2 Di- and tri-peptidal renin inhibitors MERCK & CO. INC. (US) 1985-12-04 EP claimed
EP-0157409-A2 Renin inhibitors containing 2-substituted statine MERCK & CO. INC. (US) 1985-10-09 EP claimed
EP-0156318-A2 C-terminal amide cyclic renin inhibitors containing peptide isosteres MERCK & CO. INC. (US) 1985-10-02 EP claimed
EP-0156322-A2 Renin inhibitors containing peptide isosteres MERCK & CO. INC. (US) 1985-10-02 EP claimed
EP-0129189-A2 Renin inhibitors containing a C-terminal amide cycle and compositions and combinations containing the same MERCK & CO. INC. (US) 1984-12-27 EP claimed
US-4443441-A Fixation of intraocular lenses GALIN MILES A 1984-04-17 US claimed
US-4327725-A Osmotic device with hydrogel driving member ALZA CORPORATION (US) 1982-05-04 US claimed
US-4310524-A TCA Composition and method for rapid onset antidepressant therapy RICHARDSON-MERRELL, INC. (US) 1982-01-12 US claimed
EP-0005057-A1 A material and composition for reducing blood pressure MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1979-10-31 EP claimed
US-4022893-A Treatment for hypertension MOYER JOHN H 1977-05-10 US claimed