Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27680126 | 0.90 | CTNNB1 (1.00) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL28876495 | 0.90 | CTNNB1 (1.00) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL5724 | 0.90 | CTNNB1 (1.00) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL50731 | 0.88 | CTNNB1 (0.96) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL28081666 | 0.88 | CTNNB1 (0.96) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Methyl Alcohol SCHEMBL8782982 | 0.86 | CTNNB1 (0.93) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| Hydroquinone SCHEMBL28208693 | 0.83 | CTNNB1 (0.86) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL4155251 | 0.83 | CTNNB1 (0.68) | CTNNB1SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL30775024 | 0.83 | CTNNB1 (0.68) | CTNNB1SMN1; SMN2MEN1KMT2ASIRT2 | |
| SCHEMBL4155480 | 0.83 | CTNNB1 (0.68) | CTNNB1SMN1; SMN2MEN1KMT2ASIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060566-A1 | Benzazepine derivatives as histamine h3 antagonists | HRH3, HRH4, HRH1 | CTNNB1 1777/4885SMN1; SMN2 2487/4885MEN1 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.