SCHEMBL5724145

SCHEMBL5724145

CC[C@H](C)[C@H](NC(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1)C(O[SiH](C)C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.33
OGA O60502 1/20 0.32
ABCB1 P08183 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5723881 0.93 OGA (0.34) ACACBOGAHRH3
SCHEMBL5723896 0.93 OGA (0.34) ACACBOGAHRH3
SCHEMBL5826396 0.90 OGA (0.35) ACACBOGAABCB1HRH3
SCHEMBL5724187 0.89 ACACB (0.33) ACACBOGAABCB1HRH3
SCHEMBL5724497 0.86 OGA (0.33) ACACBOGAABCB1HRH3
SCHEMBL5724503 0.86 OGA (0.33) ACACBOGAABCB1HRH3
SCHEMBL5826410 0.85 ABCB1 (0.33) ACACBOGAABCB1
SCHEMBL5723932 0.82 OGA (0.31) OGA
SCHEMBL5724101 0.82 OGA (0.37) ACACBOGAABCB1HRH3
SCHEMBL5724114 0.82 OGA (0.37) ACACBOGAABCB1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed