SCHEMBL5723896

SCHEMBL5723896

CC(C)[C@H](NC(=O)c1csc(N2CC(OS(C)(=O)=O)C2)n1)C(O[SiH](C)C)C(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OGA O60502 1/20 0.34
HRH3 Q9Y5N1 2/20 0.33
ACACB O00763 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5723881 1.00 OGA (0.34) OGAHRH3ACACB
SCHEMBL5724145 0.93 ACACB (0.33) OGAHRH3ACACB
SCHEMBL5724101 0.89 OGA (0.37) OGAHRH3ACACB
SCHEMBL5724114 0.89 OGA (0.37) OGAHRH3ACACB
SCHEMBL5724497 0.88 OGA (0.33) OGAHRH3ACACB
SCHEMBL5724503 0.88 OGA (0.33) OGAHRH3ACACB
SCHEMBL5724187 0.88 ACACB (0.33) OGAHRH3ACACB
SCHEMBL5723932 0.84 OGA (0.31) OGA
SCHEMBL5724277 0.83 OGA (0.35) OGAHRH3ACACB
SCHEMBL5723964 0.83 OGA (0.46) OGAHRH3ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1340757-B1 1-METHYLCARBAPENEM DERIVATIVES SANKYO CO (JP) 2006-10-11 EP disclosed
US-7001897-B2 1-methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2006-02-21 US disclosed
US-20040014962-A1 1-Methylcarbapenem derivatives SANKYO COMPANY, LIMITED (JP) 2004-01-22 US disclosed
EP-1340757-A1 1-METHYLCARBAPENEM DERIVATIVES Sankyo Company, Limited (JP) 2003-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014962-A1 1-Methylcarbapenem derivatives CD14, CPT1A, ACMSD OGA 3469/4885HRH3 3678/4885ACACB 74/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.