Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724315 | 0.89 | MAPT (0.52) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5366036 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5366028 | 0.84 | MAPT (0.54) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5724386 | 0.83 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL6506834 | 0.82 | MAPT (0.48) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6506827 | 0.82 | MAPT (0.48) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5364442 | 0.81 | MEN1 (0.50) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5369496 | 0.81 | MEN1 (0.50) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5359783 | 0.76 | MAPT (0.49) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL21708265 | 0.76 | MAPT (0.62) | MAPTSMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644352-A1 | PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS | Allergan, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005016917-A1 | PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS | ALLERGAN, INC. (US) | 2005-02-24 | — | — | WO | disclosed |