SCHEMBL57249

SCHEMBL57249

O=C(CCCCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 7/20 0.55
PTGS2 P35354 7/20 0.55
MGLL Q99685 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
ALDH1A1 P00352 4/20 0.50
FAAH O00519 3/20 0.50
HPGD P15428 3/20 0.50
HTT P42858 2/20 0.50
MAPT P10636 2/20 0.50
HSP90AA1 P07900 1/20 0.50
TLR9 Q9NR96 1/20 0.50
LMNA P02545 1/20 0.50
TP53 P04637 1/20 0.50
PKM P14618 1/20 0.50
XBP1 P17861 1/20 0.50
MAPK1 P28482 1/20 0.50
RECQL P46063 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GPR35 Q9HC97 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9185109 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL11033299 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL945656 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL946090 1.00 PTGS1 (0.55) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL18918259 0.98 PTGS1 (0.53) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL105903 0.94 PTGS1 (0.46) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL15578882 0.92 PTGS1 (0.48) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL15426046 0.91 PTGS1 (0.49) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL17193752 0.91 PTGS1 (0.49) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1
SCHEMBL12014013 0.91 PTGS1 (0.46) PTGS1PTGS2MGLLSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8020 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746914-A1 DRUG CONJUGATES FOR BONE MARROW PROTECTION Zymeron Corporation (US) 2026-05-27 EP claimed
CN-122011155-A Dendritic poly-L-lysine modified PACAP, and preparation method and application thereof 安徽省立医院(中国科学技术大学附属第一医院) 2026-05-12 CN claimed
EP-4719485-A1 ANTIBODY-DRUG CONJUGATES FOR TREATING INFECTIONS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) Taimed Biologics Inc. (TW) 2026-04-08 EP claimed
US-12594038-B2 Estimation of contact force of catheter expandable assembly BIOSENSE WEBSTER (ISRAEL) LTD. (IL) 2026-04-07 US claimed
EP-4688828-A1 RADIOPHARMACEUTICAL CONJUGATE COMPOUND FOR DIAGNOSIS AND/OR THERAPEUTIC USES THEREOF Jubilant DraxImage Inc. (CA) 2026-02-11 EP claimed
US-12547574-B2 I/O carrier and backplane for industrial process control systems FISHER-ROSEMOUNT SYSTEMS, INC. (US) 2026-02-10 US claimed
WO-2025235971-A1 METHODS FOR DETECTING DNA SEQUENCE VARIATION IN THICK TISSUE SECTIONS THE JOHNS HOPKINS UNIVERSITY (US) 2025-11-13 WO claimed
EP-4642491-A1 METHOD FOR GLYCOPROTEIN MODIFICATION Honeybear Biosciences Inc. (TW) 2025-11-05 EP claimed
WO-2025226837-A1 ANTI-BACTERIAL METALLOTHIONEIN ANTIBODIES AND USES THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-30 WO claimed
EP-4628492-A1 PREPARATION METHOD FOR LINKER-DRUG CONJUGATE AND INTERMEDIATE THEREOF Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd. (CN) 2025-10-08 EP claimed
US-5412087-A Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces AFFYMAX TECHNOLOGIES N.V. (AN) 1995-05-02 US claimed
EP-0649857-A1 Peptide having inflammation affinity and radioactive diagnostic containing the same NIHON MEDI-PHYSICS Co., Ltd. (JP) 1995-04-26 EP claimed
US-5264221-A Liposomes with maleimide groups bonded to thiol groups in proteins for antitumor agents MITSUBISHI KASEI CORPORATION (JP) 1993-11-23 US claimed
WO-1993022680-A1 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF OLIGONUCLEOTIDES AND OTHER BIOLOGICAL POLYMERS ON SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1993-11-11 WO claimed
EP-0526700-A2 Drug-containing protein-bonded liposome Mitsubishi Chemical Corporation (JP) 1993-02-10 EP claimed
EP-0516063-A1 Antibody-enzyme complex and enzyme immunoassay using it SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1992-12-02 EP claimed
EP-0306309-A2 Monoclonal antibodies recognizing alpha-hANP and corresponding hybridomas, their preparation and use SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1989-03-08 EP claimed
EP-0049860-B1 PROCESS FOR THE PREPARATION OF REACTIVE THYROID GLAND HORMONES T3 AND T4 DERIVATIVES THAT ARE CAPABLE OF COUPLING, AND THEIR USE Roche Diagnostics GmbH (DE) 1984-10-03 EP claimed
US-4423227-A SILYLATION, ACYLATION BOEHRINGER MANNHEIM GMBH (DE) 1983-12-27 US claimed
EP-0049860-A1 Process for the preparation of reactive thyroid gland hormones T3 and T4 derivatives that are capable of coupling, and their use Roche Diagnostics GmbH (DE) 1982-04-21 EP claimed